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VIA CNN.com:

Nearly 400 people are feared dead after a rapid series of strong earthquakes hit a mountainous and impoverished area of China’s Qinghai province early Wednesday, state-run media said.

At least 10,000 others were injured, the Xinhua news agency reported, and many victims, including school children, were buried under debris. Rescuers were struggling to clear debris with their hands and save those trapped below.

A 6.9-magnitude earthquake, as measured by the U.S. Geological Survey, struck at 7:49 a.m. local time (7:49 p.m. ET Tuesday), when many citizens were still at home and schools were beginning the day. The USGS also recorded several strong aftershocks — one of magnitude 5.8 — all within hours of the initial quake.

The epicenter was located in remote and rugged terrain, about 150 miles (240 kilometers) northwest of Qamdo, Tibet. Qinghai borders the autonomous regions of Tibet and Xingjiang and the provinces of Gansu and Sichuan.